diff --git a/runtime/autoload/dist/script.vim b/runtime/autoload/dist/script.vim
index de168f0c09..0106900f8f 100644
--- a/runtime/autoload/dist/script.vim
+++ b/runtime/autoload/dist/script.vim
@@ -4,7 +4,7 @@ vim9script
 # Invoked from "scripts.vim" in 'runtimepath'
 #
 # Maintainer:	The Vim Project <https://github.com/vim/vim>
-# Last Change:	2025 Dec 22
+# Last Change:	2026 Apr 09
 # Former Maintainer:	Bram Moolenaar <Bram@vim.org>
 
 export def DetectFiletype()
@@ -115,7 +115,7 @@ export def Exe2filetype(name: string, line1: string): string
     return 'php'
 
     # Python
-  elseif name =~ 'python'
+  elseif name =~ 'python' || (name == 'uv' && line1 =~ '\<uv run\>')
     return 'python'
 
     # Groovy
diff --git a/src/testdir/test_filetype.vim b/src/testdir/test_filetype.vim
index 7a6615531c..04036b0eb4 100644
--- a/src/testdir/test_filetype.vim
+++ b/src/testdir/test_filetype.vim
@@ -1108,7 +1108,8 @@ def s:GetScriptChecks(): dict<list<list<string>>>
     php:    [['#!/path/php']],
     python: [['#!/path/python'],
             ['#!/path/python2'],
-            ['#!/path/python3']],
+            ['#!/path/python3'],
+            ['#!/usr/bin/env -S uv run --script']],
     groovy: [['#!/path/groovy']],
     ruby:   [['#!/path/ruby']],
     javascript: [['#!/path/node'],
diff --git a/src/version.c b/src/version.c
index 70bca36892..483f55d9f6 100644
--- a/src/version.c
+++ b/src/version.c
@@ -734,6 +734,8 @@ static char *(features[]) =
 
 static int included_patches[] =
 {   /* Add new patch number below this line */
+/**/
+    327,
 /**/
     326,
 /**/